The ABCs of Solute Carriers: Physiological, Pathological and Therapeutic Implications of Human Membrane Transport proteinsIntroduction

Pflugers Arch. 2004 Feb;447(5):465-8. doi: 10.1007/s00424-003-1192-y. Epub 2003 Nov 18.

Abstract

The Human Genome Organisation (HUGO) Nomenclature Committee Database provides a list of transporter families of the solute carrier (SLC) gene series (see http://www.gene.ucl.ac.uk/nomenclature/). Currently, it includes 43 families and 298 transporter genes. This special issue features mini-reviews on each of these SLC families written by the experts in each field. A WEB site has been established (http://www.pharmaconference.org/slctable.asp) that gives the latest updates for the SLC families and their members as well as relevant links to gene databases and reviews in the literature. A list of all currently known SLC families, a discussion of additional SLC families and family members as well as a brief summary of non-SLC transporter genes is included in this introduction.

Publication types

  • Review

MeSH terms

  • Animals
  • Biological Transport / physiology
  • Cell Membrane / physiology
  • Humans
  • Membrane Transport Proteins / physiology*

Substances

  • Membrane Transport Proteins