Comparison of perivascular astrocytic structure between white matter and gray matter of rats

Brain Res. 2003 Dec 5;992(2):294-7. doi: 10.1016/j.brainres.2003.08.052.

Abstract

Regional differences in perivascular glial structures were investigated between the white matter (hippocampal fimbria, corpus callosum, cerebellar medulla) and the gray matter (cerebral cortex) of adult rats. Sparser vascular distribution, perivascular glial rows and cylinder-like segmented astrocytic endings were characteristic in the white matter. The perivascular astrocytic processes covered microvessels extensively in the white matter. Comparison of transverse microvessel sections by transmission electron microscopy (TEM) between the two sites revealed significantly larger perivascular astrocytic spaces in the white matter.

Publication types

  • Comparative Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Astrocytes / physiology
  • Astrocytes / ultrastructure*
  • Blood-Brain Barrier / physiology*
  • Brain / physiology
  • Brain / ultrastructure*
  • Cerebellum / blood supply
  • Cerebellum / cytology
  • Cerebellum / ultrastructure
  • Cerebral Cortex / blood supply
  • Cerebral Cortex / cytology
  • Cerebral Cortex / ultrastructure
  • Corpus Callosum / blood supply
  • Corpus Callosum / cytology
  • Corpus Callosum / ultrastructure
  • Dementia, Vascular / pathology
  • Dementia, Vascular / physiopathology
  • Female
  • Hippocampus / blood supply
  • Hippocampus / cytology
  • Hippocampus / ultrastructure
  • Microcirculation / physiology
  • Microcirculation / ultrastructure*
  • Microscopy, Electron
  • Nerve Fibers, Myelinated / physiology
  • Nerve Fibers, Myelinated / ultrastructure*
  • Rats
  • Rats, Inbred F344