Mesial temporal structures and comorbid anxiety in refractory partial epilepsy

J Neuropsychiatry Clin Neurosci. 2003 Fall;15(4):450-2. doi: 10.1176/jnp.15.4.450.


We used quantitative magnetic resonance imaging (MRI) to examine the mesial temporal structures in subjects with refractory partial epilepsy and comorbid anxiety and found preservation with a right-sided preponderance. The findings indicate a role for this brain region in the genesis of anxiety.

Publication types

  • Comparative Study

MeSH terms

  • Amygdala / physiopathology
  • Anxiety / etiology*
  • Case-Control Studies
  • Epilepsies, Partial / physiopathology*
  • Functional Laterality
  • Hippocampus / physiopathology
  • Humans
  • Magnetic Resonance Imaging*
  • Middle Aged
  • Sclerosis / etiology*
  • Temporal Lobe / physiopathology*