Gene Silencing in Cancer in Association With Promoter Hypermethylation

N Engl J Med. 2003 Nov 20;349(21):2042-54. doi: 10.1056/NEJMra023075.

Publication types

  • Research Support, U.S. Gov't, P.H.S.
  • Review

MeSH terms

  • Acetylation
  • Biomarkers, Tumor
  • CpG Islands / physiology
  • DNA (Cytosine-5-)-Methyltransferases / metabolism
  • DNA Methylation*
  • Gene Silencing*
  • Histones / metabolism
  • Humans
  • Neoplasms / diagnosis
  • Neoplasms / genetics*
  • Neoplasms / prevention & control
  • Promoter Regions, Genetic / genetics*

Substances

  • Biomarkers, Tumor
  • Histones
  • DNA (Cytosine-5-)-Methyltransferases