Joining the DoTS: new approach to classifying adverse drug reactions

J K Aronson; R E Ferner

doi:10.1136/bmj.327.7425.1222

Joining the DoTS: new approach to classifying adverse drug reactions

BMJ. 2003 Nov 22;327(7425):1222-5. doi: 10.1136/bmj.327.7425.1222.

Authors

J K Aronson¹, R E Ferner

Affiliation

¹ University Department of Clinical Pharmacology, Radcliffe Infirmary, Oxford, UK. jeffrey.aronson@clinpharm.ox.ac.uk

Abstract

A new classification system for adverse drug reactions based on time course and susceptibility as well as dose responsiveness should improve drug development and management of adverse reactions

Publication types

Review

MeSH terms

Dose-Response Relationship, Drug
Drug Interactions
Drug-Related Side Effects and Adverse Reactions / classification*
Humans
Risk Factors
Time Factors