The effects of weight reduction on the rehabilitation of patients with knee osteoarthritis and obesity

Arthritis Care Res. 2000 Dec;13(6):398-405. doi: 10.1002/1529-0131(200012)13:6<398::aid-art10>;2-e.


Objective: To evaluate the effect of weight reduction on the rehabilitation of patients with knee osteoarthritis and obesity.

Methods: A total of 126 patients with bilateral knee osteoarthritis and obesity were classified into 3 groups by their stages of osteoarthritis. Each group was divided into subgroups a, b, and c. The subjects in subgroup a received weight reduction treatment, those in subgroup b received weight reduction and electrotherapy modalities, and those in subgroup c received electrotherapy modalities to relieve pain.

Results: Pain reduction, weight reduction, ambulation speed, and changes of Lequesne's index were greater in patients in subgroups a and b than in subgroup c after treatment. Although the last pain scores in subgroup b were less than those in subgroup a, as measured by a visual analog scale (VAS), there was no significant difference between their functional status. Significant pain relief (VAS < 2) and an acceptable functional status (Lequesne's index < 7) were indicated when weight reduction was more than 15% and 12%, respectively, of the initial body weight of the individual.

Conclusion: Weight reduction was found to be a practical adjuvant treatment in the rehabilitation of patients with knee osteoarthritis.

Publication types

  • Clinical Trial
  • Controlled Clinical Trial

MeSH terms

  • Acupuncture Therapy
  • Adult
  • Aged
  • Analysis of Variance
  • Combined Modality Therapy
  • Disability Evaluation
  • Exercise Therapy
  • Female
  • Humans
  • Male
  • Middle Aged
  • Nutritional Sciences / education
  • Obesity / complications
  • Obesity / prevention & control*
  • Osteoarthritis, Knee / etiology
  • Osteoarthritis, Knee / rehabilitation*
  • Pain / diagnosis
  • Pain / etiology
  • Pain Management
  • Pain Measurement
  • Patient Education as Topic
  • Severity of Illness Index
  • Transcutaneous Electric Nerve Stimulation
  • Treatment Outcome
  • Weight Loss*