Effects of effervescent creatine, ribose, and glutamine supplementation on muscular strength, muscular endurance, and body composition

J Strength Cond Res. 2003 Nov;17(4):810-6. doi: 10.1519/1533-4287(2003)017<0810:eoecra>2.0.co;2.


The purpose of this study was to examine the effects of a combination of effervescent creatine, ribose, and glutamine on muscular strength (MS), muscular endurance (ME) and body composition (BC) in resistance-trained men. Subjects were 28 men (age: 22.3 +/- 1.7 years; weight: 85.8 +/- 12.1 kg; height: 1.8 +/- 0.1 m) who had 2 or more years of resistance-training experience. A double blind, randomized trial was completed involving supplementation or placebo control and a progressive resistance-training program for 8 weeks. Dependent measures were assessed at baseline and after 8 weeks of resistance training. Both groups significantly improved MS and ME while the supplement group significantly increased body weight and fat-free mass. Control decreased body fat and increased fat-free mass. This study demonstrated that the supplement group did not enhance MS, ME, or BC significantly more than control after an 8-week resistance-training program.

Publication types

  • Clinical Trial
  • Randomized Controlled Trial

MeSH terms

  • Adult
  • Analysis of Variance
  • Body Composition / drug effects*
  • Creatine / pharmacology*
  • Dietary Supplements*
  • Double-Blind Method
  • Glutamine / pharmacology*
  • Humans
  • Male
  • Muscle, Skeletal / drug effects*
  • Physical Endurance / drug effects
  • Ribose / pharmacology*
  • Weight Lifting / physiology


  • Glutamine
  • Ribose
  • Creatine