Orthotopic liver transplantation for hepatic GVHD following allogeneic BMT for chronic myeloid leukaemia

D I Marks; B Dousset; A Robson; G Imvrios; J A Buckels; E Elias; J M Neuberger; C Foster; R Batchelor; J M Goldman

Orthotopic liver transplantation for hepatic GVHD following allogeneic BMT for chronic myeloid leukaemia

Bone Marrow Transplant. 1992 Nov;10(5):463-6.

Authors

D I Marks¹, B Dousset, A Robson, G Imvrios, J A Buckels, E Elias, J M Neuberger, C Foster, R Batchelor, J M Goldman

Affiliation

¹ Department of Haematology, Hammersmith Hospital, London, UK.

PMID: 1464011

Abstract

A 21-year-old man who had an HLA-identical sibling donor BMT for chronic myeloid leukaemia developed grade IV acute GVHD of the liver that was unresponsive to corticosteroids and anti-IL2 receptor monoclonal antibody. He was treated with an orthotopic liver transplant and is currently well 6 months later with normal liver function and no evidence of GVHD in the transplanted liver.

Publication types

Case Reports
Research Support, Non-U.S. Gov't

MeSH terms

Adult
Bone Marrow Transplantation / adverse effects*
Graft vs Host Disease / etiology
Graft vs Host Disease / surgery*
Humans
Leukemia, Myelogenous, Chronic, BCR-ABL Positive / surgery*
Liver Diseases / etiology
Liver Diseases / surgery*
Liver Transplantation*
Male