Central nervous system tumours in adolescents

Eur J Cancer. 2003 Dec;39(18):2643-50. doi: 10.1016/j.ejca.2003.09.003.


Adolescents with brain tumours have been, and in most cases still are, haphazardly assigned, on referral, to either 'paediatric' or 'adult'-based treatment centres. In this age group, there is therefore a history of inconsistent treatment, delivery of inappropriate 'maturity-related' care and a reduced chance of gathering vital biological, clinical and treatment-related information germane to this group of patients and their tumours. These days, adolescents with brain tumours should be actively targeted for recruitment into clinical trials and admission into dedicated neuro-oncology centres or programmes that can deliver the necessary and age appropriate multidisciplinary management.

Publication types

  • Review

MeSH terms

  • Adolescent
  • Adult
  • Brain Neoplasms / therapy*
  • Clinical Protocols
  • Germinoma / therapy*
  • Glioma / therapy*
  • Humans
  • Internet
  • Medulloblastoma / therapy*
  • Palliative Care
  • Patient Care Team
  • Treatment Failure