The csgD Promoter, a Control Unit for Biofilm Formation in Salmonella Typhimurium

Res Microbiol. 2003 Dec;154(10):659-67. doi: 10.1016/j.resmic.2003.08.005.

Abstract

Expression of cellulose and curli fimbriae in Salmonella typhimurium is dependent on the transcriptional regulator CsgD. Transcription of csgD itself is influenced by a variety of regulatory stimuli. Complex nucleoprotein arrangements modulate the transcriptional activity of csgD and trigger the transition between the planktonic status and biofilm formation.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Bacterial Proteins / genetics
  • Bacterial Proteins / metabolism
  • Biofilms / growth & development*
  • Gene Expression Regulation, Bacterial
  • Promoter Regions, Genetic*
  • Salmonella typhimurium / genetics
  • Salmonella typhimurium / growth & development*
  • Salmonella typhimurium / metabolism
  • Trans-Activators / genetics*
  • Trans-Activators / metabolism
  • Transcription, Genetic

Substances

  • Bacterial Proteins
  • Trans-Activators