SOLVE and RESOLVE: Automated Structure Solution, Density Modification and Model Building

J Synchrotron Radiat. 2004 Jan 1;11(Pt 1):49-52. doi: 10.1107/s0909049503023938. Epub 2003 Nov 28.

Abstract

The software SOLVE and RESOLVE can carry out all the steps in macromolecular structure solution, from scaling and heavy-atom location through phasing, density modification and model-building in the MAD, SAD and MIR cases. SOLVE uses scoring scheme to convert the decision-making in macromolecular structure solution to an optimization problem. RESOLVE carries out the identification of NCS, density modification and automated model-building. The procedure is fully automated and can function at resolutions as low as 3 A.

Publication types

  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Algorithms*
  • Binding Sites
  • Computer Simulation
  • Crystallography / methods*
  • Databases, Protein*
  • Macromolecular Substances
  • Models, Molecular*
  • Protein Binding
  • Protein Conformation
  • Proteins / chemistry*
  • Sequence Analysis, Protein
  • Software*
  • User-Computer Interface

Substances

  • Macromolecular Substances
  • Proteins