A multiple logistic regression analysis of in-hospital factors related to survival at six months in patients resuscitated from out-of-hospital ventricular fibrillation

Resuscitation. 2003 Dec;59(3):319-28. doi: 10.1016/s0300-9572(03)00238-7.


Introduction: The impact of the immediate in-hospital post-resuscitation care after out-hospital cardiac arrest is not well known. Based on treatment variables and laboratory findings a multiple logistic regression model was created for the prediction of survival at 6 months from the event.

Materials and methods: A retrospective study of the hospital charts of patients successfully resuscitated and treated in one of three community hospitals from 1998 to 2000. In addition to several pre-hospital variables, the mean 72 h values of clinical features such as blood pressure, blood glucose concentration and initiated treatment used, were included in a forward multiple logistic regression model predicting survival at 6 months from the event.

Results: The charts of 98 out of a total of 102 patients were sufficiently complete and included in the analysis. Variables independently associated with survival were age, delay before a return of spontaneous circulation, mean blood glucose and serum potassium, and the use of beta-blocking agents during post-resuscitation care. When those patients who were assigned a 'do not attempt to resuscitate' (DNAR) order during the first 72 h of treatment were excluded from the analysis blood glucose, blood potassium and the use beta-blocking agents remained independently associated with survival.

Conclusion: This study suggests that in-hospital factors are associated with survival from out-of-hospital cardiac arrest. The mean blood glucose and serum potassium during the first 72 h of treatment and the use of beta-blocking agents were significantly and independently associated with survival.

Publication types

  • Comparative Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adrenergic beta-Antagonists / therapeutic use
  • Aged
  • Analysis of Variance
  • Blood Glucose / analysis
  • Cardiopulmonary Resuscitation / statistics & numerical data*
  • Cause of Death
  • Emergency Medical Services / methods*
  • Female
  • Finland / epidemiology
  • Heart Arrest / mortality*
  • Heart Arrest / prevention & control
  • Hospital Mortality / trends*
  • Hospitalization
  • Hospitals, Community / statistics & numerical data*
  • Humans
  • Logistic Models
  • Male
  • Middle Aged
  • Multivariate Analysis
  • Potassium / blood
  • Retrospective Studies
  • Risk Factors
  • Survival Analysis
  • Time Factors
  • Ventricular Fibrillation / diagnosis
  • Ventricular Fibrillation / mortality*
  • Ventricular Fibrillation / therapy*


  • Adrenergic beta-Antagonists
  • Blood Glucose
  • Potassium