Unraveling the functions of glycosyltransferase family 47 in plants

Trends Plant Sci. 2003 Dec;8(12):565-8. doi: 10.1016/j.tplants.2003.10.003.

Abstract

The function of glycosyltransferases (GTs) from family GT47 was first identified in animal exostosins as beta-glucuronyltransferase involved in the synthesis of heparan sulfate. Two recent papers report the functions of two plant members in this family as a pectin beta-glucuronyltransferase and a xyloglucan beta-galactosyltransferase. These findings greatly extend our understanding of the biological functions of family GT47 and also represent an important leap toward the molecular dissection of cell wall biosynthesis.

Publication types

  • Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

  • Amino Acid Sequence
  • Cell Wall / chemistry
  • Cell Wall / enzymology
  • Cell Wall / genetics
  • Galactosyltransferases / genetics
  • Galactosyltransferases / metabolism
  • Galactosyltransferases / physiology
  • Glucans / biosynthesis
  • Glucuronosyltransferase / genetics
  • Glucuronosyltransferase / physiology
  • Glycosyltransferases / genetics
  • Glycosyltransferases / physiology*
  • Molecular Sequence Data
  • Multigene Family / genetics
  • Pectins / biosynthesis
  • Phylogeny
  • Plant Proteins / genetics
  • Plant Proteins / physiology
  • Plants / enzymology*
  • Plants / genetics
  • Plants / metabolism
  • Sequence Homology, Amino Acid
  • Xylans / biosynthesis

Substances

  • Glucans
  • Plant Proteins
  • Xylans
  • xyloglucan
  • Pectins
  • Glycosyltransferases
  • Galactosyltransferases
  • MUR3 protein, Arabidopsis
  • Glucuronosyltransferase