Abstract
The effect of vasoactive intestinal polypeptide (VIP) on the contractile activity of the urinary bladder was investigated in the rat. VIP caused a weak contraction and a small potentiation of carbachol- and acetylcholine-induced contractions. The present results may provide the evidence that VIP could be a modulator in the urinary bladder.
MeSH terms
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Acetylcholine / pharmacology
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Animals
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Carbachol / pharmacology
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In Vitro Techniques
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Male
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Muscle Contraction / drug effects*
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Muscle, Smooth / drug effects
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Muscle, Smooth / physiology*
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Rats
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Urinary Bladder / drug effects
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Urinary Bladder / physiology*
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Vasoactive Intestinal Peptide / pharmacology*
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Vasoactive Intestinal Peptide / physiology
Substances
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Vasoactive Intestinal Peptide
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Carbachol
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Acetylcholine