Functional classification of the microbial feruloyl esterases

Appl Microbiol Biotechnol. 2004 Feb;63(6):647-52. doi: 10.1007/s00253-003-1476-3. Epub 2003 Dec 6.


Feruloyl esterases have potential uses over a broad range of applications in the agri-food industries. In recent years, the number of microbial feruloyl esterase activities reported has increased and, in parallel, even more related protein sequences may be discerned in the growing genome databases. Based on substrate utilisation data and supported by primary sequence identity, four sub-classes have been characterised and termed type-A, B, C and D. The proposed sub-classification scheme is discussed in terms of the evolutionary relationships existing between carbohydrate esterases.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Bacteria / enzymology
  • Carboxylic Ester Hydrolases / classification*
  • Carboxylic Ester Hydrolases / genetics
  • Carboxylic Ester Hydrolases / metabolism
  • Fungi / enzymology
  • Phylogeny
  • Sequence Homology
  • Substrate Specificity


  • Carboxylic Ester Hydrolases
  • feruloyl esterase