Conservative treatment may be beneficial for young women with atypical endometrial hyperplasia or endometrial adenocarcinoma

Fertil Steril. 2003 Dec;80(6):1315-24. doi: 10.1016/s0015-0282(03)01183-x.


Objective: To evaluate whether an alternative treatment to radical hysterectomy exists for young women with endometrial adenocarcinoma.

Design: A review of the literature (70 articles) plus personal results.

Setting: University hospital.

Patient(s): Women with atypical endometrial hyperplasia or adenocarcinoma.

Main outcome measure(s): The recurrence rate and the pregnancy rate after conservative therapy.

Conclusion(s): Conservative treatment of well-differentiated stage I endometrial adenocarcinoma can be considered in young patients, with close surveillance to diagnose any possible recurrence.

Publication types

  • Review

MeSH terms

  • Adenocarcinoma / diagnosis
  • Adenocarcinoma / therapy*
  • Adult
  • Diagnosis, Differential
  • Endometrial Hyperplasia / diagnosis
  • Endometrial Hyperplasia / therapy*
  • Endometrial Neoplasms / diagnosis
  • Endometrial Neoplasms / therapy*
  • Female
  • Humans
  • Prognosis
  • Reproducibility of Results
  • Risk Factors