Tuberculous meningitis with acellular cerebrospinal fluid in AIDS patients

AIDS. 1992 Oct;6(10):1165-7. doi: 10.1097/00002030-199210000-00016.


Objective: To describe the clinical manifestations of tuberculous meningitis in HIV-positive patients with acellular cerebrospinal fluid (CSF).

Design: Retrospective analysis of case reports.

Methods: Four HIV-positive patients with acellular CSF and tuberculous meningitis are reported.

Results: Clinical presentation did not indicate meningeal infection in three of the four cases, and CSF tests were unusual in all cases. Two patients were diagnosed only after death.

Conclusions: Acellular CSF may obstruct the diagnosis of tuberculous meningitis in AIDS patients.

Publication types

  • Case Reports

MeSH terms

  • Acquired Immunodeficiency Syndrome / complications*
  • Acquired Immunodeficiency Syndrome / diagnosis
  • Adult
  • Cerebrospinal Fluid / cytology*
  • Humans
  • Male
  • Middle Aged
  • Tuberculosis, Meningeal / complications*