The histologic type and stage distribution of ovarian carcinomas of surface epithelial origin

Int J Gynecol Pathol. 2004 Jan;23(1):41-4. doi: 10.1097/01.pgp.0000101080.35393.16.


Advances over the past decade suggest a need to reassess the distribution of ovarian surface epithelial tumors. A series of 220 consecutive invasive ovarian carcinomas, including carcinosarcomas and peritoneal carcinomas, was reviewed. Notable findings include: 7% of tumors were carcinosarcomas; 22% of cases of peritoneal serous carcinomatosis were of peritoneal origin; <3% of cases were mucinous carcinomas; and only one malignant Brenner tumor (0.5%) and no pure transitional cell carcinomas were identified. If peritoneal carcinomas, carcinosarcomas, and mixed carcinomas with a serous component are combined with serous carcinomas, this group accounts for 78% of all cases and 87% of advanced stage cases, suggesting a greater uniformity to epithelial ovarian cancer than previously appreciated.

Publication types

  • Comparative Study

MeSH terms

  • Carcinoma / pathology*
  • Female
  • Humans
  • Neoplasm Staging
  • Ovarian Neoplasms / pathology*
  • Retrospective Studies