In vitro snake venom detoxifying action of some marine algae of Gulf of Mannar, south-east coast of India

Phytother Res. 2003 Dec;17(10):1217-9. doi: 10.1002/ptr.1342.

Abstract

The extract of the brown seaweed Padina boergesenii and the red seaweed Hypnea valentiae was found to detoxify (in vitro) the venom of Naja nigricollis. There was a remarkable reduction in the mortality of albino mice after intraperitoneal (i.p.) administration of reconstituted venom with the extract compared to those challenged with the venom only. The survival of the animals exposed to the venom incubated with the different concentrations of the extract was used as the in vitro detoxification parameter.

MeSH terms

  • Animals
  • Antivenins / administration & dosage
  • Antivenins / pharmacology*
  • Antivenins / therapeutic use
  • Elapid Venoms / antagonists & inhibitors*
  • Eukaryota*
  • India
  • Injections, Intraperitoneal
  • Mice
  • Phytotherapy*
  • Plant Extracts / administration & dosage
  • Plant Extracts / pharmacology*
  • Plant Extracts / therapeutic use
  • Seaweed

Substances

  • Antivenins
  • Elapid Venoms
  • Plant Extracts