Treatment of herpes simplex virus infections

Antiviral Res. 2004 Feb;61(2):73-81. doi: 10.1016/j.antiviral.2003.09.006.


Herpes simplex virus (HSV) types 1 and 2 are ubiquitous organisms that cause infections in human populations throughout the world. The clinical manifestations of HSV infections are varied, ranging from asymptomatic disease to life-threatening illness in neonates and immunocompromised hosts. This article will review the common presentations for HSV disease and the current recommendations for the treatment of these infections. A detailed summary of the antiviral drugs used to treat HSV infections is also presented.

Publication types

  • Review

MeSH terms

  • Antiviral Agents / therapeutic use
  • Female
  • Herpes Simplex / diagnosis*
  • Herpes Simplex / drug therapy*
  • Herpes Simplex / etiology
  • Herpesvirus 1, Human
  • Herpesvirus 2, Human
  • Humans
  • Immunocompromised Host
  • Infant, Newborn
  • Male
  • Viral Vaccines / isolation & purification


  • Antiviral Agents
  • Viral Vaccines