Issues in diagnostic testing and monitoring in HIV/viral hepatitis co-infection

J HIV Ther. 2003 Nov;8(4):89-95.

Abstract

Co-infection with HIV and hepatitis B (HBV)/ hepatitis C virus (HCV) occurs commonly due to similar routes of transmission. Both hepatotropic viruses can cause a severe clinical picture in HIV-infected individuals with rapid progression of liver disease, cirrhosis and increased mortality. Fortunately, treatment options of HBV and HCV are becoming well established and may have a clinical impact in slowing disease progression. This, coupled with the fact that highly active antiretroviral therapy (HAART) has increased the life expectancy of HIV-infected patients stresses the importance of management of concurrent illnesses such as HBV and HCV infection, taking into consideration pharmacokinetic interaction with components of HAART regimens.

Publication types

  • Review

MeSH terms

  • Antibodies, Viral / blood
  • Antiretroviral Therapy, Highly Active
  • Antiviral Agents / therapeutic use
  • DNA, Viral / chemistry
  • DNA, Viral / genetics
  • HIV / growth & development
  • HIV Infections / complications*
  • HIV Infections / diagnosis*
  • HIV Infections / drug therapy
  • Hepacivirus / genetics
  • Hepacivirus / isolation & purification
  • Hepatitis B virus / genetics
  • Hepatitis B virus / isolation & purification
  • Hepatitis B, Chronic / complications*
  • Hepatitis B, Chronic / diagnosis*
  • Hepatitis B, Chronic / drug therapy
  • Hepatitis C, Chronic / complications*
  • Hepatitis C, Chronic / diagnosis*
  • Hepatitis C, Chronic / drug therapy
  • Humans
  • Polymerase Chain Reaction
  • Reagent Kits, Diagnostic

Substances

  • Antibodies, Viral
  • Antiviral Agents
  • DNA, Viral
  • Reagent Kits, Diagnostic