Validation of prediction of kindergarten-age school-readiness scores of nondisabled survivors of moderate neonatal encephalopathy in term infants

Can J Public Health. 1992 Jul-Aug;83 Suppl 2:S51-7.


Outcome studies of nonmalformed term infants with neonatal encephalopathy associated with late fetal and/or early neonatal distress show those in the severe category die or become disabled; 18% in the moderate category become disabled and of the nondisabled, greater than 40% have school-readiness delay. Predictive indices for kindergarten-age learning ability obtained from obstetrical/neonatal and family/social data were developed for 71 nondisabled survivors of moderate neonatal encephalopathy born in 1974-79 (Cohort I). Predicted outcome was compared to actual outcome of a second cohort of neonates with the same diagnosis, born in 1982-86 (Cohort II); comparison groups for both cohorts were tested. School-readiness scores from Cohort II were similar to Cohort I and both were below respective comparison groups. Prediction for the nondelayed was 68% to 95%; for the delayed 7% to 29%, affected by the lower sample size available for this category. Predicted scores were within 0.5 SD of actual scores for 80% of not delayed children. Nondisabled survivors predicted to do very well can be discharged from follow-up; others with moderate or severe neonatal encephalopathy should receive ongoing assessment.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Brain Damage, Chronic / psychology
  • Brain Diseases / psychology*
  • Child, Preschool
  • Cohort Studies
  • Humans
  • Infant, Newborn
  • Learning*
  • Neuropsychological Tests
  • Predictive Value of Tests
  • Reproducibility of Results
  • Schools, Nursery
  • Set, Psychology*
  • Social Environment