The utility of muscle biopsy

Curr Neurol Neurosci Rep. 2004 Jan;4(1):81-6. doi: 10.1007/s11910-004-0017-5.

Abstract

Despite major advances in molecular genetics, histopathologic evaluation of muscle biopsy specimens continues to provide important diagnostic information in patients with suspected muscle diseases and in patients with vasculitic neuropathies. Muscle biopsy specimens are used in diagnosing many inherited as well as inflammatory and toxic myopathies. Furthermore, the study of muscle histopathology can also enhance our understanding of disease pathogenesis.

Publication types

  • Review

MeSH terms

  • Biopsy / trends
  • Biopsy, Needle / trends
  • Diagnosis, Differential
  • Humans
  • Muscle Proteins / deficiency
  • Muscle Proteins / genetics
  • Muscle, Skeletal / pathology*
  • Muscle, Skeletal / physiopathology
  • Muscular Diseases / genetics
  • Muscular Diseases / pathology*
  • Muscular Diseases / physiopathology
  • Mutation / genetics
  • Neuromuscular Diseases / genetics
  • Neuromuscular Diseases / pathology*
  • Neuromuscular Diseases / physiopathology
  • Predictive Value of Tests

Substances

  • Muscle Proteins