Fetal origin of the GATA1 mutation in identical twins with transient myeloproliferative disorder and acute megakaryoblastic leukemia accompanying Down syndrome

Blood. 2004 Jan 1;103(1):366. doi: 10.1182/blood-2003-09-3219.
No abstract available

Publication types

  • Case Reports
  • Letter
  • Twin Study

MeSH terms

  • Amino Acid Sequence
  • Base Sequence
  • DNA Mutational Analysis
  • DNA, Complementary / genetics
  • DNA-Binding Proteins / genetics*
  • Down Syndrome / complications*
  • Erythroid-Specific DNA-Binding Factors
  • Female
  • GATA1 Transcription Factor
  • Humans
  • Infant, Newborn
  • Leukemia, Megakaryoblastic, Acute / complications*
  • Leukemia, Megakaryoblastic, Acute / genetics*
  • Molecular Sequence Data
  • Mutation*
  • Myeloproliferative Disorders / complications*
  • Myeloproliferative Disorders / congenital
  • Myeloproliferative Disorders / genetics*
  • Transcription Factors / genetics*

Substances

  • DNA, Complementary
  • DNA-Binding Proteins
  • Erythroid-Specific DNA-Binding Factors
  • GATA1 Transcription Factor
  • GATA1 protein, human
  • Transcription Factors