Bowel preparation for the total colonoscopy by 2,000 ml of balanced lavage solution (Golytely) and sennoside

Gastroenterol Jpn. 1992 Dec;27(6):728-33. doi: 10.1007/BF02806525.


One of disadvantages of the Golytely preparation is that examinees have to drink as much as 4,000 ml of Golytely. To overcome this disadvantage, we designed a modified preparation regimen in which examinees have to drink only 2,000 ml of Golytely by taking sennoside orally. Bowel preparation was carried out in 297 examinees by this modified method. Examinees ate their usual diet and took 36 mg of sennoside orally on the night before the examination. On the day of the examination, the examinees drank a total of 2,000 ml of Golytely. No severe complications were noted and 97% of the examinees were able to drink the dose of 2,000 ml. Subjects who had also experienced bowel preparation by the modified method of Brown were asked to compare the two regimens, and only 1% preferred Brown's method while 73% preferred bowel preparation by our Golytely method. The result of bowel preparation by this method was excellent or good in 90 to 97% of the subjects at all sites in the colon and rectum. We conclude that bowel preparation for total colonoscopy using 2,000 ml of Golytely and sennoside is superior because it is highly acceptable to the examinees and provides excellent gut irrigation.

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Aged, 80 and over
  • Anthraquinones / administration & dosage*
  • Anthraquinones / adverse effects
  • Cathartics / administration & dosage*
  • Cathartics / adverse effects
  • Colonoscopy*
  • Electrolytes / administration & dosage*
  • Electrolytes / adverse effects
  • Female
  • Humans
  • Male
  • Middle Aged
  • Polyethylene Glycols / administration & dosage*
  • Polyethylene Glycols / adverse effects
  • Senna Extract
  • Sennosides
  • Therapeutic Irrigation / methods*


  • Anthraquinones
  • Cathartics
  • Electrolytes
  • Golytely
  • Sennosides
  • Polyethylene Glycols
  • Senna Extract