Papular mucinosis is a rare, idiopathic cutaneous mucinosis that is typically chronic and progressively severe. We present a case of a 59-year-old woman with a 6-month history of a dramatic papular eruption on her face and neck, with no associated internal organ involvement. A biopsy specimen demonstrated increased dermal mucin with associated plump fibroblasts, consistent with a diagnosis of papular mucinosis. Multiple therapeutic interventions were unsuccessful, and after 2 years the lesions resolved spontaneously without treatment. During the following 3 years, the patient has had no recurrence of disease.