Giant-cell reparative granuloma of the temporal bone: a case report and review of the literature

Ear Nose Throat J. 2003 Dec;82(12):926-9, 933-4, 936-7.


Giant-cell reparative granuloma (GCRG) is an unusual, non-neoplastic fibrous lesion that most often arises in the mandible and maxilla. GCRG of the temporal bone is exceedingly rare. To the best of our knowledge, only 17 cases have been previously reported in the international medical literature. Although no case of metastasis has been reported, this malignancy can be locally aggressive, and it often recurs following incomplete excision. We report the case of a young woman with a very large GCRG of the right temporal bone. We discuss the clinical picture, differential diagnosis, histologic evaluation, appearance on computed tomography and magnetic resonance imaging, and treatment options. We also review the cases of temporal bone GCRG that have been reported in the literature so far.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Adolescent
  • Bone Diseases / diagnostic imaging*
  • Bone Diseases / pathology*
  • Bone Diseases / surgery
  • Female
  • Granuloma, Giant Cell / diagnostic imaging*
  • Granuloma, Giant Cell / pathology*
  • Granuloma, Giant Cell / surgery
  • Humans
  • Radiography
  • Temporal Bone / diagnostic imaging*
  • Temporal Bone / pathology*
  • Temporal Bone / surgery