Abstract
[reaction: see text] A diastereoselective total synthesis of securinine in optically pure form was achieved by employing ring-closing metathesis of the corresponding dienyne compound as a key step.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Alkaloids / chemical synthesis*
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Azepines / chemical synthesis*
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Heterocyclic Compounds, 4 or More Rings / chemical synthesis*
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Heterocyclic Compounds, Bridged-Ring
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Lactones / chemical synthesis*
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Models, Chemical
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Molecular Structure
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Pipecolic Acids / chemistry
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Piperidines / chemical synthesis*
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Stereoisomerism
Substances
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Alkaloids
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Azepines
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Heterocyclic Compounds, 4 or More Rings
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Heterocyclic Compounds, Bridged-Ring
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Lactones
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Pipecolic Acids
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Piperidines
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securinine