Prevalence of idiopathic hypertrophic cardiomyopathy in China: a population-based echocardiographic analysis of 8080 adults

Am J Med. 2004 Jan 1;116(1):14-8. doi: 10.1016/j.amjmed.2003.05.009.


Purpose: To determine the prevalence of hypertrophic cardiomyopathy in China.

Methods: This epidemiologic investigation was performed in 8080 adults from nine communities across nine provinces in China from October 2001 to February 2002, using a multistage, random sample design. Hypertrophic cardiomyopathy was defined as nondilated ventricular hypertrophy, documented by echocardiography, that was not caused by any known cardiac or systemic disease.

Results: Of the 4064 men and 4016 women who were screened, 13 (0.16%; 9 men and 4 women) had definite echocardiographic evidence for hypertrophic cardiomyopathy. The age- and sex-adjusted prevalence was about 80 per 100,000 adults.

Conclusion: Hypertrophic cardiomyopathy is not rare in China. Based on the estimated prevalence, there are at least 1 million cases in China.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Cardiomyopathy, Hypertrophic / diagnostic imaging
  • Cardiomyopathy, Hypertrophic / epidemiology*
  • China / epidemiology
  • Cross-Sectional Studies
  • Echocardiography, Doppler
  • Female
  • Heart Septum / diagnostic imaging
  • Humans
  • Incidence
  • Male
  • Mass Screening / statistics & numerical data
  • Middle Aged
  • Sampling Studies
  • Ventricular Outflow Obstruction / diagnostic imaging
  • Ventricular Outflow Obstruction / epidemiology