The IKK NF-kappa B system: a treasure trove for drug development

Nat Rev Drug Discov. 2004 Jan;3(1):17-26. doi: 10.1038/nrd1279.
No abstract available

Publication types

  • Review

MeSH terms

  • Adjuvants, Immunologic / chemistry
  • Adjuvants, Immunologic / pharmacology
  • Animals
  • Anti-Inflammatory Agents / chemistry
  • Anti-Inflammatory Agents / pharmacology
  • Drug Design*
  • Enzyme Inhibitors* / chemistry
  • Enzyme Inhibitors* / pharmacology
  • Humans
  • I-kappa B Kinase
  • Molecular Structure
  • NF-kappa B / antagonists & inhibitors*
  • NF-kappa B / physiology
  • Protein-Serine-Threonine Kinases / antagonists & inhibitors*
  • Protein-Serine-Threonine Kinases / physiology
  • Signal Transduction

Substances

  • Adjuvants, Immunologic
  • Anti-Inflammatory Agents
  • Enzyme Inhibitors
  • NF-kappa B
  • Protein-Serine-Threonine Kinases
  • CHUK protein, human
  • I-kappa B Kinase
  • IKBKB protein, human
  • IKBKE protein, human