A bioassay for derivatives of qinghaosu (artemisinin)

Trop Med Parasitol. 1992 Sep;43(3):195-6.

Abstract

A sensitive bioassay was developed for measuring the serum antimalarial activity for qinghaosu (artemisinin) derivatives. This should assist in the formulation of optimum regimens for the treatment of P. falciparum malaria.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Antimalarials / administration & dosage
  • Antimalarials / blood*
  • Antimalarials / pharmacokinetics
  • Artemisinins*
  • Biological Assay
  • Drugs, Chinese Herbal / administration & dosage
  • Drugs, Chinese Herbal / analysis*
  • Drugs, Chinese Herbal / pharmacokinetics
  • Injections, Intramuscular
  • Saimiri
  • Sesquiterpenes / administration & dosage
  • Sesquiterpenes / blood*
  • Sesquiterpenes / pharmacokinetics

Substances

  • Antimalarials
  • Artemisinins
  • Drugs, Chinese Herbal
  • Sesquiterpenes
  • artemisinine