Consecutive transfer of day 3 embryos and of day 5-6 blastocysts increases overall pregnancy rates associated with blastocyst culture

J Assist Reprod Genet. 2003 Nov;20(11):461-4. doi: 10.1023/b:jarg.0000006708.26464.23.

Abstract

Purpose: To investigate whether the consecutive embryo transfer of day 3 embryos and of blastocyst protects against failure to reach embryo transfer and provides additional pregnancies.

Methods: An embryo transfer was performed on day 3 following which all remaining embryos were cultured to the blastocyst stage for a possible second transfer.

Results: One hundred and forty-two patients were selected for extended culture. Thirty-two of these patients did not develop blastocysts in culture, however, there were 12 pregnancies achieved in this group.

Conclusions: The consecutive transfer of day 3 embryos and blastocysts can prevent the total loss of a cycle when embryos fail to develop to the blastocyst stage in culture and thereby provide additional pregnancies.

MeSH terms

  • Adult
  • Blastocyst / physiology*
  • Culture Techniques
  • Embryo Implantation*
  • Embryo Transfer*
  • Embryo, Mammalian / cytology*
  • Embryo, Mammalian / physiology
  • Female
  • Fertilization in Vitro
  • Humans
  • Male
  • Pregnancy / physiology*
  • Pregnancy Rate