Development of a depressed left ventricular ejection fraction in patients with left ventricular hypertrophy and a normal ejection fraction

Am J Cardiol. 2004 Jan 15;93(2):234-7. doi: 10.1016/j.amjcard.2003.09.050.

Abstract

The progression from concentric left ventricular (LV) hypertrophy to heart failure has not been well defined. Of 159 predominantly hypertensive African-American patients with LV hypertrophy and a normal ejection fraction (EF), 28 (18%) developed a reduced EF after a median follow-up of approximately 4 years. Risk factors for this outcome included a history of coronary artery disease, pulmonary edema seen on a chest x-ray, or a subsequent myocardial infarction.

MeSH terms

  • African Americans
  • Coronary Disease / epidemiology
  • Disease Progression
  • Echocardiography
  • Female
  • Follow-Up Studies
  • Heart Failure / epidemiology
  • Humans
  • Hypertension / epidemiology
  • Hypertension / physiopathology*
  • Hypertrophy, Left Ventricular / diagnostic imaging*
  • Logistic Models
  • Male
  • Middle Aged
  • Myocardial Infarction / epidemiology
  • Pulmonary Edema / epidemiology
  • Retrospective Studies
  • Risk Factors
  • Stroke Volume / physiology*
  • Time Factors
  • Ventricular Dysfunction, Left / diagnostic imaging*