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. 2004 Jan;24(1):57-8.

[Experimental Study of the Effect of Astragalus Membranaceus Against Herpes Simplex Virus Type 1]

[Article in Chinese]
Affiliations
  • PMID: 14724098

[Experimental Study of the Effect of Astragalus Membranaceus Against Herpes Simplex Virus Type 1]

[Article in Chinese]
Yan Sun et al. Di Yi Jun Yi Da Xue Xue Bao. .

Abstract

Objective: To study the inhibitory effects of Astragalus membranaceus on herpes simplex virus type 1(HSV-1).

Methods: In the 2BS cells infected with HSV-1, the antiviral effect of Astragalus membranaceus decoction was investigated by observing the inhibition of HSV-1-induced cytopathic effect in response to treatment with the decoction.

Results: The half inhibition concentration (IC50) and minimal inhibition concentration (MIC) of Astragalus membranaceus were 0.98 and 1.95 g/ml respectively, with the therapeutic index (TI) of 128.

Conclusion: Astragalus membranaceus has obvious HSV-1-inhibiting efficacy and low cytotoxicity.

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