The pleural fissures, formed by a double layer of visceral pleura, represent extensions of the pleural space between lobes of the lungs. The fissures are frequently an anatomic barrier to the spread of inflammatory or neoplastic disease. Identification of the fissures is important for the accurate localization of lung parenchymal or pleural pathology. The plain radiographic and computed tomographic (CT) imaging of normal and variant fissural anatomy, as well as of some abnormalities that may affect the fissures will be reviewed and illustrated.