Skip to main page content
Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
, 4 (10), 357-65

Pores for Thought: Nuclear Pore Complex Proteins


Pores for Thought: Nuclear Pore Complex Proteins

M P Rout et al. Trends Cell Biol.


Nuclear pore complexes (NPCs) are enormous macromolecular structures that mediate the active exchange of proteins and RNPs between the nucleus and cytoplasm. Recent work has resulted in a windfall of identified NPC polypeptides, many with unique sequences. Several of the proteins have been shown to be part of extended cytoplasmic and nucleoplasmic NPC filaments. Biochemical, structural and genetic studies on NPC proteins are just beginning to allow an understanding of how they associate into a functional organelle.

Similar articles

See all similar articles

Cited by 111 PubMed Central articles

See all "Cited by" articles

LinkOut - more resources