Dual roles for transcription and translation factors in the RNA storage particles of Xenopus oocytes

S R Tafuri; A P Wolffe

doi:10.1016/0962-8924(93)90080-k

Dual roles for transcription and translation factors in the RNA storage particles of Xenopus oocytes

Trends Cell Biol. 1993 Mar;3(3):94-8. doi: 10.1016/0962-8924(93)90080-k.

Authors

S R Tafuri¹, A P Wolffe

Affiliation

¹ Laboratory of Molecular Embryology, National Institute of Child Health and Human Development, National Institutes of Health, Bldg 6, Rm B1A-13, Bethesda, MD 20892, USA.

PMID: 14731778
DOI: 10.1016/0962-8924(93)90080-k

Abstract

During oogenesis, Xenopus laevis utilizes homologues of normal transcription or translation factors to sequester a variety of RNA molecules into ribonucleoprotein storage particles. This remarkable adaptive function for a diverse group of regulatory molecules allows the oocyte to stockpile macromolecules for use during embryogenesis. We discuss the special features of these nucleic acid-binding proteins and the insights into their structure and function that follow from their dual biological role.