Nuclear transport: a guide to import receptors

Trends Cell Biol. 1992 May;2(5):123-7. doi: 10.1016/0962-8924(92)90083-y.

Abstract

After synthesis in the cytoplasm, nuclear proteins traverse the nuclear envelope as a result of the specific recognition of nuclear localization signals by import. Various approaches have now uncovered a range of proteins with at least some of the characteristics expected of import receptors. This article focuses on early steps in the nuclear import of proteins and surveys the recently identified candidate import receptors.