The physiological regulation of thirst and fluid intake

News Physiol Sci. 2004 Feb:19:1-6. doi: 10.1152/nips.01470.2003.


Thirst is important for maintaining body fluid homeostasis and may arise from deficits in either intracellular or extracellular fluid volume. Neural signals arising from osmotic and hormonal influences on the lamina terminalis may be integrated within the brain, with afferent information relayed from intrathoracic baroreceptors via the hindbrain to generate thirst.

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, P.H.S.
  • Review

MeSH terms

  • Animals
  • Brain / physiology*
  • Drinking / physiology*
  • Humans
  • Thirst / physiology*
  • Water-Electrolyte Balance / physiology*