Why do we not all have proteinuria? An update of our current understanding of the glomerular barrier

News Physiol Sci. 2004 Feb;19:7-10. doi: 10.1152/nips.01461.2003.


The key question is not why some patients have proteinuria but rather why not all people have it. In the present review, we will present an update on the glomerular barrier after the recent breakthroughs in podocyte biology. In particular, we will discuss the role of the endothelium, which seems to be a neglected part of the glomerular membrane.

Publication types

  • Review

MeSH terms

  • Animals
  • Endothelium / physiology
  • Humans
  • Kidney Glomerulus / physiology*
  • Proteinuria / metabolism*
  • Proteinuria / physiopathology*