The tethered Biginelli condensation in natural product synthesis

Zachary D Aron; Larry E Overman

doi:10.1039/b309910e

The tethered Biginelli condensation in natural product synthesis

Chem Commun (Camb). 2004 Feb 7:(3):253-65. doi: 10.1039/b309910e. Epub 2003 Oct 27.

Authors

Zachary D Aron¹, Larry E Overman

Affiliation

¹ Department of Chemistry, 516 Rowland Hall, University of California, Irvine, CA 92697-2025, USA.

PMID: 14740029
DOI: 10.1039/b309910e

Abstract

This review describes the development of the tethered Biginelli condensation and its application to the total synthesis of structurally complex, bioactive guanidine alkaloids.

Publication types

Research Support, Non-U.S. Gov't
Review

MeSH terms

Alkaloids / chemical synthesis*
Alkaloids / chemistry
Animals
Biological Factors / chemical synthesis*
Biological Factors / chemistry
Guanidine / chemical synthesis*
Guanidine / chemistry
Models, Molecular
Molecular Structure
Porifera

Substances

Alkaloids
Biological Factors
Guanidine