Sex-related differences in the cognitive consequences of early left-hemisphere lesions

J Clin Exp Neuropsychol. 1992 Sep;14(5):738-48. doi: 10.1080/01688639208402859.


Epileptic patients who had undergone the carotid amytal test were assessed on a variety of measures of verbal and nonverbal ability. All patients had left-hemisphere dysfunction early in life, before 1 year of age. In males, such damage results in generalized cognitive retardation regardless of the status of the cerebral speech pattern. In females, intellectual retardation is linked specifically to a shift in speech processes. This sex-related difference in behavioral outcome may reflect interruption at different maturational stages and/or the influences of the immediate hormonal milieu.

Publication types

  • Comparative Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Cognition / physiology*
  • Cognition Disorders / complications
  • Epilepsy / complications
  • Epilepsy / psychology*
  • Female
  • Humans
  • Language
  • Male
  • Memory / physiology
  • Psychological Tests
  • Psychomotor Performance / physiology
  • Sex Characteristics
  • Speech / physiology
  • Wechsler Scales