Objective: To investigate the clinical relevant factors causing laryngeal cancer postoperative recurrence and analysis the reasons of treatment failure.
Methods: Totally, 574 cases of laryngeal cancer from 1958 to 1999 treated in ENT department of PLA general hospital were retrospectively reviewed. All the patients were observed for 3 years postoperatively, and finally 56 cases of the recurrence were diagnosed. We analyzed the factors possibly causing the recurrence including age, sex, history, time in hospital, smoke, grade of pathology, combination, tumor stage, transfusion, radiotherapy, operation manners and cervical lymph metastasis node grade.
Results: By statistic analysis, tumor grade (P = 0.0002), operation (P = 0.0017), transfusion (P = 0.0001), radiotherapy (P = 0.0001) and cervical lymphatic metastasis node grade(P = 0.0228) have significant meaning with laryngeal cancer postoperative recurrence.
Conclusion: Tumor grade, transfusion, radiotherapy, operation and cervical lymph metastasis node grade are main factors which may cause neoplasm postoperative recurring.