Mucoepidermoid carcinoma arising within nevus sebaceus of Jadassohn

J Cutan Pathol. 2003 Nov;30(10):652-5. doi: 10.1034/j.1600-0560.2003.00124.x.


Background: Nevus sebaceus (NS) of Jadassohn is a common congenital lesion associated with numerous benign and malignant tumors. However, mucoepidermoid carcinoma (MEC) has not been described in association with NS.

Methods: We describe an unusual case of MEC arising within NS.

Results: A 72-year-old man presented with an enlarging plaque on his forehead, along the hairline. Physical examination revealed a mounded, erythematous lesion that was completely excised. Histological evaluation revealed a typical MEC with areas of squamous and adenomatous differentiation with foci of typical intermediate cells.

Conclusion: The diagnosis of MEC is an important one, because it portends a poor prognosis, requiring long follow-up. This is, to our knowledge, the first report of MEC arising within NS.

Publication types

  • Review

MeSH terms

  • Aged
  • Carcinoma, Mucoepidermoid / pathology*
  • Humans
  • Male
  • Neoplasms, Multiple Primary / pathology*
  • Nevus / pathology*
  • Skin Neoplasms / pathology*
  • Sweat Gland Neoplasms / pathology*