GeneNote: whole genome expression profiles in normal human tissues

Orit Shmueli; Shirley Horn-Saban; Vered Chalifa-Caspi; Michael Shmoish; Ron Ophir; Hila Benjamin-Rodrig; Marilyn Safran; Eytan Domany; Doron Lancet

doi:10.1016/j.crvi.2003.09.012

GeneNote: whole genome expression profiles in normal human tissues

C R Biol. 2003 Oct-Nov;326(10-11):1067-72. doi: 10.1016/j.crvi.2003.09.012.

Authors

Orit Shmueli¹, Shirley Horn-Saban, Vered Chalifa-Caspi, Michael Shmoish, Ron Ophir, Hila Benjamin-Rodrig, Marilyn Safran, Eytan Domany, Doron Lancet

Affiliation

¹ Department of Molecular Genetics, The Weizmann Institute of Science, 76100 Rehovot, Israel. orit.shmueli@weizmann.ac.il

PMID: 14744114
DOI: 10.1016/j.crvi.2003.09.012

Abstract

A novel data set, GeneNote (Gene Normal Tissue Expression), was produced to portray complete gene expression profiles in healthy human tissues using the Affymetrix GeneChip HG-U95 set, which includes 62 839 probe-sets. The hybridization intensities of two replicates were processed and analyzed to yield the complete transcriptome for twelve human tissues. Abundant novel information on tissue specificity provides a baseline for past and future expression studies related to diseases. The data is posted in GeneNote (http://genecards.weizmann.ac.il/genenote/), a widely used compendium of human genes (http://bioinfo.weizmann.ac.il/genecards).

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Gene Expression*
Genome, Human*
Humans