Thirty female subjects examined in the first three months of pregnancy took part in the study. Ten of these suffered from severe gravidic hyperemesis, while twenty had a physiological pregnancy. All subjects with hyperemesis and six controls were subjected to measurement of cortisolaemia at the following times: 8, 12, 16, 20, 24 and 4.00 so as to obtain the circadian curve of the hormone, measurement of T3 and T4 and of TSH. The Cattell test in form C was carried out in all patients. The results obtained evidenced a global increase in the production of cortisol in the group of hyperemetic women, with maintenance of the circadian rhythm. The Cattell test identified characteristic personality traits in the subjects suffering from hyperemesis compared to the controls.