Tuberculous fasciitis in scleroderma

Clin Rheumatol. 2004 Feb;23(1):66-8. doi: 10.1007/s10067-003-0811-5. Epub 2003 Nov 12.

Abstract

A 25-year old woman visited the hospital because of a painful swelling for 20 days in the midposterior portion of her right thigh. She had been diagnosed with systemic sclerosis and treated for 10 months. An MRI scan of the right thigh showed diffuse fascial thickening and involved the superficial portion of thigh muscles, which were hyperintense on the T(2)-weighted image. A biopsy of the involved muscles revealed chronic granulomatous inflammation with several acid-fast bacilli on a Ziehl-Neelsen stain. We here report a case of tuberculous fasciitis manifest with painful swelling of the midposterior muscles of the right thigh without pulmonary tuberculosis in a patient with scleroderma.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Antitubercular Agents / therapeutic use
  • DNA, Bacterial / analysis
  • Drug Therapy, Combination
  • Fasciitis / complications*
  • Fasciitis / microbiology
  • Fasciitis / pathology
  • Female
  • Humans
  • Immunocompromised Host
  • Magnetic Resonance Imaging
  • Muscle, Skeletal / microbiology
  • Muscle, Skeletal / pathology
  • Mycobacterium tuberculosis / genetics
  • Mycobacterium tuberculosis / isolation & purification
  • Mycobacterium tuberculosis / pathogenicity
  • Polymerase Chain Reaction
  • Scleroderma, Systemic / complications*
  • Scleroderma, Systemic / microbiology
  • Scleroderma, Systemic / pathology
  • Thigh / pathology
  • Tuberculosis / complications*
  • Tuberculosis / drug therapy
  • Tuberculosis / pathology

Substances

  • Antitubercular Agents
  • DNA, Bacterial