Epidermal growth factor in topical treatment following epikeratoplasty

Ophthalmologica. 1992;205(3):121-4. doi: 10.1159/000310325.


The efficacy of epidermal growth factor (EGF) in reducing the healing time of the cornea after an epikeratoplasty has been evaluated in an open study in two groups of patients. The time required for complete reepithelialization of the cornea was recorded, and the data obtained were analyzed statistically. In the EGF group the reepithelialization was significantly faster than in the control group. These results indicate that EGF is effective in reducing the reepithelialization time of the cornea after an epikeratoplasty.

MeSH terms

  • Aphakia, Postcataract / surgery*
  • Cornea / drug effects
  • Epidermal Growth Factor / administration & dosage*
  • Epikeratophakia / methods*
  • Epithelium / drug effects
  • Humans
  • Keratoconus / surgery*
  • Ophthalmic Solutions
  • Wound Healing / drug effects*


  • Ophthalmic Solutions
  • Epidermal Growth Factor