Marrow cells as progenitors of lung tissue

Blood Cells Mol Dis. Jan-Feb 2004;32(1):95-6. doi: 10.1016/j.bcmd.2003.09.021.


There is accumulating evidence showing that marrow-derived cells can engraft as differentiated epithelial cells of various tissues, including the lung. These findings challenge long-held views regarding the basic biology of stem cells. Elucidating the fundamental mechanisms controlling these processes is the major challenge of this field. Regardless, these experiments suggest new strategies for the treatment of chronic diseases.

Publication types

  • Review

MeSH terms

  • Bone Marrow Cells / cytology*
  • Cell Culture Techniques / methods
  • Humans
  • Lung / pathology*
  • Lung Injury
  • Stem Cell Transplantation
  • Stem Cells / cytology*