Use of gadolinium as an intraarterial contrast agent for pediatric neuroendovascular procedures

J Neurosurg. 2004 Feb;100(2 Suppl Pediatrics):150-5. doi: 10.3171/ped.2004.100.2.0150.


Object: The safety and efficacy of Gd as an intraarterial contrast agent for pediatric neuroendovascular procedures were investigated.

Methods: The authors retrospectively reviewed data regarding pediatric neuroendovascular procedures performed during a 1-year period. Seventeen procedures involving the use of gadodiamide in nine pediatric patients were identified. All angiographic images were of diagnostic quality but usually required minimal postimage processing. In time-consuming cases, the use of gadodiamide allowed the procedure to continue when the dosage of iodinated contrast approached a toxicity level and would have otherwise prompted termination of the procedure. This likely reduced the total number of procedures necessary. No adverse events due to the intraarterial use of gadodiamide were identified.

Conclusions: Gadodiamide appears to be a safe and effective contrast agent for pediatric patients.

MeSH terms

  • Angiography, Digital Subtraction / methods*
  • Carotid-Cavernous Sinus Fistula / diagnostic imaging
  • Carotid-Cavernous Sinus Fistula / therapy
  • Central Nervous System Vascular Malformations / diagnostic imaging
  • Central Nervous System Vascular Malformations / therapy
  • Cerebral Angiography / methods*
  • Cerebral Veins / abnormalities
  • Cerebral Veins / diagnostic imaging
  • Child
  • Child, Preschool
  • Contrast Media* / adverse effects
  • Creatinine / blood
  • Embolization, Therapeutic / methods*
  • Female
  • Gadolinium DTPA* / adverse effects
  • Humans
  • Infant
  • Infant, Newborn
  • Infusions, Intra-Arterial
  • Intracranial Arteriovenous Malformations / diagnostic imaging*
  • Intracranial Arteriovenous Malformations / therapy*
  • Male
  • Pia Mater / blood supply
  • Sensitivity and Specificity
  • Telangiectasia, Hereditary Hemorrhagic / diagnostic imaging*
  • Telangiectasia, Hereditary Hemorrhagic / therapy*


  • Contrast Media
  • gadodiamide
  • Creatinine
  • Gadolinium DTPA